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The IVD is a fibrocartilaginous tissue that sits between and connects two adjacent vertebral bodies and is composed of the external AF, the inner gel-like center NP, and the cartilaginous endplates that serve as a connection to the vertebrae

They are usually taken at night, because the body releases its largest growth hormone pulse during early deep sleep

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As such, tirzepatide may offer significant potential value for patients, payers, and society, and the findings highlight the importance of considering long-term value rather than upfront drug costs alone