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This concern is particularly relevant for hormone-sensitive tissues like breast, prostate, and colon

For patients experiencing gastrointestinal side effects , practical strategies can minimise fluid loss and associated thirst: Eat smaller, more frequent meals to reduce nausea Avoid high-fat, spicy, or heavily seasoned foods that may exacerbate gastrointestinal symptoms Consider oral rehydration solutions if diarrhoea is problematic Take Ozempic as prescribed, following the recommended dose escalation schedule to allow the body to adjust gradually If unable to keep fluids down or experiencing ongoing vomiting or diarrhoea, seek clinical advice promptly as there is a risk of dehydration and acute kidney injury

By tracking what you eat and your symptoms, you may notice patterns

As expected, 13-month-old KO animals were still glucose intolerant (Fig