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The in vitro RET assays showed that MPTP significantly increased RET, as indicated by the significantly increased ROS and decreased NAD + /NADH ratio, which were dose-dependently rescued in mitochondria isolated from the substantia nigra (Fig

In non-human research, it has shown relevance in the regulation of gene expression tied to regeneration, collagen production, and oxidative stress recovery

Researchers planning new work should review the most current literature before designing protocols, with attention to the gap between preclinical breadth and clinical-trial depth

Culture of leukemia cell lines on stromal cell line KM102 does not affect proliferation, chemosensitivity or apoptosis inducibility