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Diabetes mellitus is a metabolic disease that is characterized by persistent elevations in blood glucose, or hyperglycemia

As the half-life of retatrutide is 6 days, once weekly administration was sufficient with as expected gastrointestinal disturbance being the most common side effect and occurring in 63% of those on retatrutide, 60% on dulaglutide, and 54% of the placebo cohort [63]