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Shop Medications , GLP-1 medications work by mimicking a hormone that helps control blood sugar and appetite
In the ARC, activation of the JAK2/STAT3 pathway by leptin inhibits the activity of neurons expressing NPY and AgRP, which are orexigenic (appetite-stimulating)
This is why it's associated with a wider range of effects, including increased libido (via MC4R) and appetite suppression
These findings have generated significant interest within healthy aging and longevity research
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