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The 28-day rule is based on contamination risk, not chemical stability, which persists beyond this period
B12 replacement may be important when deficiency is present, but it is not a universal treatment for chronic pain, fatigue, neuropathy, autoimmune disease, or neurologic symptoms
Researchers see sterile water, normal saline, and bacteriostatic water on the shelf and wonder if they are interchangeable
doi:10.1080/10408398.2015.1117413
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