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The article names anticholinergics, opioids, and some antiemetics as drug classes that worsen motility, and says these interactions must be evaluated before starting

Lab handling should follow established protocols for research compounds, including personal protective equipment and contamination prevention measures

10.1016/s2213-8587(18)30268-7 57 NielsenM

If you were a lung specialist and you saw 15 cases of pneumonia every day, five days a week, for 10 years, you could see pneumonia a mile away and take care of it