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Although many treatments effective in animal models of IRI have failed to translate into clinical use, glucagon-like peptide 1 (GLP-1) and the GLP-1 receptor (GLP-1R) agonist exenatide have shown benefits in IRI in both animal models (47) and small early-phase clinical trials (8, 9)

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doi: 10.2147/JEP.S35396

The short-chain amino acids serve as the building blocks of proteins and key signaling molecules in the body, helping regulate several functions, including immune response, muscle protein synthesis and hormonal cycles