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Recent phase 2 and phase 3 clinical trials have established the therapeutic value of various GLP-1 RAs in improving liver histology and metabolic parameters in patients with MASH
It has not been studied in people who also take a short-acting (prandial) insulin
Serious but rare adverse effects associated with GLP-1 receptor agonists include: Pancreatitis : If suspected, the medication should be discontinued immediately
However, more detailed mechanistic studies have shown that protein nitration by peroxynitrite requires transition metals, such as ferrous iron
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