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A small percentage may notice: + Mild tingling or flushing on application + Temporary breakout shift (usually resolves in 12 weeks) + Short-term textural change as cell turnover increases Use with caution or skip if you have a known copper allergy or Wilson's disease (a copper metabolism disorder)
Ternette, N
(4) Research has demonstrated that NNMT inhibition results in increased intracellular nicotinamide and SAM levels
Starting at lower doses allows assessment of individual tolerance and response before potentially increasing the dose
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