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For example, the Wegovy (semaglutide) prescribing information and Zepbound (tirzepatide) prescribing information describe stepwise start low and go slow titration to a maintenance dose that was tested in clinical trials and approved by regulators.[3,4] A microdose schedule is different and always off-label
2 Apolzan, J.W., LaRose, J.G., Anton, S.D
Theres no one-size-fits-all best GLP-1 drug for everyone
Whether this translates to meaningfully better outcomes depends on the complete formulations being compared
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