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Gastrointestinal effects Nausea, the most common side effect, tends to reappear during dose escalation periods
Compared to other weight loss drugs, using GLP-1 agonists increases the risk of pancreatitis (inflammation of the pancreas) by 9 times, bowel obstruction (blockage of the small or large intestines) by 4.5 times, and gastroparesis (a condition that slows or stops the movement of food from the stomach to the small intestine) by 3.6 times
10.1016/s0140-6736(73)91602-4 Lancet
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