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Secondary HRP-linked, Alexa Fluor 488-conjugated and FITC-conjugated antibodies were from Sigma Aldrich, Abcam, and Becton, Dickinson & Company, respectively

Future studies are warranted to further define how ER stress and subsequent downstream disruptions induced by the secretory demands of the beta-cell can influence autoreactive T cell responses and beta-cell vulnerability in T1D ( Figure 1 )

Lyophilized Dihexa powder should be stored sealed in its original reagent vial at -20C for long-term preservation

There is no reaction in glycolysis in which carbon dioxide is produced, and this suggests that there must be some other pathway of glucose metabolism in the erythrocyte, in which carbon-1 of glucose is released as carbon dioxide