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Although AR gene and protein expression in male mouse gastrocnemius is dynamic and has been shown to increase from E18.5 to 3-months of age [87] and decrease from 3- to 18-months of age [88], lifespan data observing changes in AR expression across multiple muscles in males and females is limited

Patients with a history of glucose intolerance or uncontrolled diabetes require careful monitoring because elevated GH can affect insulin sensitivity

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These individuals are often left with excess skin not only in the abdominal region but in the back and flanks as well