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These findings suggest that the additional GCG agonism in cotadutide provides direct metabolic benefits to hepatocytes beyond those achievable through GLP-1 receptor activation alone, even when caloric restriction is matched [43]
4-10 GLP-1 agonists have been associated with a slight increase in acute gallbladder disease and (when used in higher doses to treat obesity) with suicidal ideation and minor increases in heart rate
Does insurance make GLP-1s affordable
Lancet Gastroenterol Hepatol 2023;8(4):321331
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