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This local inflammatory response not only directly impairs the physiological functions of key cellular components in the penis but also forms a vicious cycle with oxidative stress and tissue remodeling, ultimately contributing to the development and progression of ED ( Figure 3 )
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All statistical tests were two-sided and used a significance level of P 4000 observations additionally including an additional sample with data collected in subjects still available at 6-year follow-up
Obesity Reviews (2004) 7
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