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HIF-1 ameliorates tubular injury in diabetic nephropathy via HO-1-mediated control of mitochondrial dynamics
Effective at improving glycaemic control with a low intrinsic risk of hypoglycaemia and the potential for weight reduction, this agent class is an important addition to the prescribing armamentarium
Additional studies describe exploratory evaluation of intracellular signaling dynamics, NAD-related metabolic networks, and methylation-associated processes examined in non-clinical research settings
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