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Materials and methods: T2D-related genes were identified by NN interrogation of UK BioBank sequencing data
Understanding that curve is particularly important for a multi-agonist like retatrutide, since its triple pathway activation may produce nonlinear effects that differ from those of single pathway agents
70 For example, compound 2j, a triazole-containing derivative, has demonstrated high potency and comparable efficacy to danuglipron in preclinical studies, suggesting it could serve as a lead compound for further development
Weight regain can begin soon after discontinuation
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