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Some drugs, including proton pump inhibitors (PPIs) and histamine 2 receptor antagonists (H2RAs) are acid-inhibiting, impairing the release of dietary B12 from food proteins, thus producing risk of B12 deficiency (Lam et al., 2013)

Managing missed doses appropriately is important for maintaining therapeutic benefits while avoiding adverse effects from irregular dosing patterns

In animal-based foods, vitamin B12 binds to the protein molecules