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That last qualifier matters: an open-label study with exploratory endpoints generates encouraging signals and answers a specific dosing question, but it cannot substitute for the randomized, controlled cirrhosis-outcome trial now underway in Phase 3
Wireko, A.A
Apoptosis 18:11881200 Bourassa P, Alata W, Tremblay C, Paris-Robidas S, Calon F (2019) Transferrin receptor-mediated uptake at the bloodbrain barrier is not impaired by Alzheimers disease neuropathology
William Johnson, Atlanta Live Interview
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