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In this disorder, the immune system produces antibodiesprimarily thyroid peroxidase (TPO) antibodies and thyroglobulin antibodiesthat attack the thyroid gland, leading to progressive destruction of thyroid tissue

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Scientific Activity In biochemical and cell models, 5-AMINO-1MQ inhibits NNMT, reducing methyl transfer from S-adenosylmethionine to nicotinamide and altering downstream methyl-donor and nicotinamide metabolite pools