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Conversely, injectable formulations may remain preferable for patients who prioritize once-weekly dosing over daily administration, individuals whose schedules or circumstances make consistent empty-stomach morning dosing challenging, those for whom predictable high bioavailability is clinically important, patients with gastrointestinal conditions potentially affecting oral drug absorption, and individuals who previously responded well to injectable therapy and see no reason to change administration routes

We don't recommend it during pregnancy or breastfeeding, or for clients with kidney disease, congestive heart failure, certain electrolyte disorders, or G6PD deficiency

Some individuals feel appetite suppression by day 34, while others need 1014 days to notice a shift

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