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This chronic, systemic depletion allows environmental toxins and latent, dormant infections (such as EBV or human herpesviruses) to reactivate and accumulate, continuously driving immune dysfunction, mast cell activation syndrome (MCAS), and unrelenting fatigue
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Further evidence for this hypothesis comes from recent yeast two-hybrid studies performed with enzymes from sweet peony, where the arGST Ps GSTF3 was found to interact with Ps DFR, the dihydroflavonol reductase catalysing the formation of 3,4- cis -leucocyanidin ( 6 ) 47
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