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Raun and colleagues (Eur J Endocrinol, 1998) characterised it as the first growth hormone releasing peptide with selectivity approaching that of GHRH itself, reporting growth hormone release without the accompanying ACTH and cortisol elevation seen with earlier compounds in the class such as GHRP-6 and hexarelin
Future studies should focus on elucidating the mechanisms of action of these antioxidants and exploring their potential synergistic effects with other therapeutic interventions to optimize clinical outcomes in patients with AP
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