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Lee et al.'s RCT validated these mechanisms in real patients using topical application

The potential limitations of certain studies may include the period of the research, as it may not adequately capture the long-term effects and potential negative effects of GLP-1 agonists

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Further, this trend was similarly observed in three distinct genetic subsets: in only protein-coding genes (18,713 genes) ( Figure 1e ), in the highest variable genes (2,000 genes) ( Figure 1f ), and in a set of previously identified (31) pan-immune-related genes (2,565 genes) ( Figure 1g )