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This results in the body having a build-up of phenylalanine
It also explains the absence of a necrotic core in melanoma, even in the avascular solid tumour phase
Recent studies have also demonstrated that exendin-4 is mediated by Ca 2+ /calmodulin (CaM)-dependent protein kinase kinase/CAM-dependent protein kinase IV/prolactin regulatory element binding (CaMKK/CaMKIV/PREB) pathway increases liver ABCA1 expression and reduces cholesterol accumulation [71]
Mech Ageing Dev 2000
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