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Published: Aug 13, 2025 Written by Klarity Editorial Team Published: Aug 13, 2025 Key takeaway: Joint pain during GLP-1 treatment particularly with tirzepatide is a recognized side effect linked to rapid fat loss, muscle changes, and inflammatory responses

Adopting a healthy lifestyle, including regular exercise and a nutritious diet, can help you achieve the best possible Semaglutide results

Research indicates that intravenous, liposomal and sublingual (applied under the tongue) methods of supplementation may be better choices over oral supplementation because they are not broken down during digestion which can prevent adequate absorption

Treatment duration differs significantly between the two options