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Table 1 Large-scale clinical trials of GLP-1RAs for the incidence of adverse cardiorenal outcomes

Diabetes 63:33463358 Kooijman S, Wang Y, Parlevliet ET et al (2015) Central GLP-1 receptor signalling accelerates plasma clearance of triacylglycerol and glucose by activating brown adipose tissue in mice

Any patient on this combination should be checking blood pressure and resting heart rate at minimum weekly, with clear thresholds established for when to reduce or discontinue one or both medications

This process creates a slower and more controlled release of the stimulant compared to medications that contain active amphetamine directly