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Low glutathione levels are not just linked to aging, but also to higher levels of oxidative damage and lower levels of intracellular antioxidants, which are commonly found in aged individuals (3)
Cells acquire cysteine mainly by macrophage and lymphocyte uptake, and impaired immune responses are associated with a reduction in GSH concentration (Drge and Breitkreutz, 2000
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RPE cells: Diverse receptor expression including growth factor receptors (EGFR, FGFR, PDGFR), cytokine receptors, integrin adhesion receptors
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