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Basically, during metabolism, some proteins and fats are broken down by Vitamin B12 so that they could be converted to energy
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Yes, vitamin B12 works well with other treatments
Given that arguably the most important reactions within neuronal cells is the production of creatine for energy transfer, in limited methylation, due to lower B12, Choline would be "Sacrificed" in order to produce the Methyl group for the conversion of homocysteine to methionine, for the ultimate production of S-Adenosylmethionine, and the production of creatine
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