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Some combinations are used in clinical practice, such as phentermine with semaglutide or metformin with a GLP-1 agonist
Clinical trials have consistently shown significant reductions in body weight, often in the range of 15.8% or 33.7 lbs., when GLP-1 medications are combined with a healthy diet and exercise
The FDA approved higher-dose oral semaglutide for chronic weight management in early 2026
She reviews the patients other medications and decides whether adding GLP-1s will do more harm than good
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