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therefore, cross-population or cross-dose extrapolation should be made cautiously, and our results do not establish or imply efficacy in non-diabetic populations or at other doses

Amid payer hesitancy to reimburse in the commercial, Medicare and Medicaid markets, we observe that some insurers are making bariatric surgery more accessible than GLP-1 drugs

Pros of naturally boosting GLP-1: No side effects No risk of long-term dependency Minimal cost with no barriers to care Provides benefits beyond GLP-1 activity (due to lifestyle changes in diet) Easy to incorporate into any lifestyle Cons of natural GLP-1: Natural GLP-1 persists for a short amount of time in the bloodstream (a few minutes) Effects vary from person to person Results arent as fast or as dramatic Can be more difficult to see dramatic and rapid results with diet and lifestyle changes alone Note: Because GLP-1 production happens naturally, there are no negative effects per se

Ill see patients with underlying thyroid disease, underlying autoimmune disease, underlying neuroendocrine disease, Dr