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The process of the removal of old erythrocytes from the circulation is also known as senescence, and similar to eryptosis, this process may be preferentially executed due to oxidative stress, hyperosmolarity, and energy depletion [24, 134]
Conclusion: While L-carnitine has been studied for its potential benefits, the evidence is mixed, and more research is needed to fully understand its effects
doi:10.1007/s00394-023-03241-6
Areas of risk include affordability as coverage of these drugs means payment upfront with health and other social benefits accruing over decades
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