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doi: 10.1210/endo.142.12.8522
It inhibits the reuptake of dopamine (DA), norepinephrine (NE), and serotonin (5-HT), leading to prolonged monoaminergic neurotransmission
Subcutaneous administration in normal and metabolically dysregulated mice significantly inhibits NNMT activity in metabolically active tissues (adipose, liver, muscle), increases systemic NAD+ levels, enhances mitochondrial function, and improves energy metabolism
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