The condition is more prevalent in males and presents as insidious onset pain at the proximal insertion site of the quadriceps tendon over the patella (20% of cases), pain at the inferior pole of the patella (70% of cases), or less commonly, pain at the tibial tuberosity (10%), which may increase during physical activity and digital pressure [4,5,6]
Despite early scientific interest, no major modern clinical development program, large contemporary randomized trials, or high-quality meta-analyses were identified
Users consistently emphasize the importance of verifying third-party testing through Certificates of Analysis showing greater than 98% purity, preferably 99% or higher
Check the powder color (should be blue to blue-purple), look for a third-party COA, verify HPLC testing, ensure the packaging is amber glass, and buy only from suppliers that disclose concentration and batch numbers