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According to research from the CDC, gout prevalence continues to rise alongside obesity rates
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( F ) Nest-building score after 12 and 24 hours upon provision of cotton-pressed nestlets for 12- to 18-week-old mice ( n = 712 per group)
[5961] With increasing attention on the metabolic role of MSTN, a study demonstrated that inhibition of MSTN ameliorated type 1 diabetes in mice by improving insulin sensitivity and enhancing the expression of Glut1 and Glut4 glucose transporters in skeletal muscle.[62] This was found to be the same in humans as elevated circulating MSTN levels have also been found in patients with type 1 diabetes.[63] Collectively, these observations highlight the therapeutic potential of targeting MSTN for the treatment of metabolic disorders, including obesity and diabetes
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