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[7] [8] Prescription and administration: Once B12 deficiency is confirmed, GPs prescribe hydroxocobalamin injections according to standardised protocols: Standard loading regimen: 1mg intramuscularly three times weekly for two weeks Neurological involvement: 1mg intramuscularly on alternate days until no further improvement Maintenance therapy: 1mg every three months for life in pernicious anaemia or malabsorption conditions (or every two months if there was neurological involvement) Injections are typically administered by practice nurses at GP surgeries
The right choice depends on whether the injury is discrete and localized or diffuse and multi-site
They also worry that when patients receive drugs online from compounding pharmacies, they may not get the same level of guidance about how to take the drugs or what to expect from the compounded drug providers as they would get from a clinician
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