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When a mixture containing the recombinant protein is passed through the column, only the proteins with the His-tag will bind to the resin, while other proteins are washed away
People who used GLP-1 RAs like Ozempic or Saxenda and experienced stomach paralysis (gastroparesis) or vision loss (NAION) have begun filing GLP-1 lawsuits against the drugs manufacturers
From that, Novo developed liraglutide, the lab-made imitation of GLP-1
The GIP receptor has additional effects on glucose metabolism, appetite signaling, and energy expenditure compared to GLP-1 alone
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