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A 2025 systematic review and meta-analysis published on PubMed found that GLP-1 RAs were superior to placebo in reducing AHI in patients with OSA and obesity, with additional benefits including reduced body weight, lower blood pressure, and improved cardiometabolic risk markers

AMPK downstream of GLP-1 can rapidly inhibit PARP activity and reduce its ability to regulate downstream genes (Gongol et al., 2013

73 Liu YY, Brent GA

This alarming figure is a result of the aging population, which is more likely to develop T2D, together with population-wide lifestyle changes, and also reflects the fact that T2D is being diagnosed earlier and, with advances in management strategies, patients are living longer [1]